Functional Overload Increases β Myosin Heavy Chain Promoter Activity in a Rodent Fast Muscle through the proximal MCAT (βe3) Site
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Functional overload increases -MHC promoter activity in rodent fast muscle via the proximal MCAT ( e3) site
Giger, Julia M., Fadia Haddad, Anqi X. Qin, and Kenneth M. Baldwin. Functional overload increases -MHC promoter activity in rodent fast muscle via the proximal MCAT ( e3) site. Am J Physiol Cell Physiol 282: C518–C527, 2002. First published October 24, 2001; 10.1152/ ajpcell.00444.2001.—Functional overload (OL) of the rat plantaris muscle by the removal of synergistic muscles induces a shift in...
متن کاملDivergence in species and regulatory role of -myosin heavy chain proximal promoter muscle-CAT elements
Tsika, Richard W., John McCarthy, Natalia Karasseva, Yangsi Ou, and Gretchen L. Tsika. Divergence in species and regulatory role of -myosin heavy chain proximal promoter muscle-CAT elements. Am J Physiol Cell Physiol 283: C1761–C1775, 2002. First published August 22, 2002; 10.1152/ajpcell.00278.2002.—We examined the functional role of distinct muscle-CAT (MCAT) elements during nonweight-bearing...
متن کاملDivergence in species and regulatory role of beta -myosin heavy chain proximal promoter muscle-CAT elements.
We examined the functional role of distinct muscle-CAT (MCAT) elements during non-weight-bearing (NWB) regulation of a wild-type 293-base pair beta-myosin heavy chain (beta MyHC) transgene. Electrophoretic mobility shift assays (EMSA) revealed decreased NTEF-1, poly(ADP-ribose) polymerase, and Max binding at the human distal MCAT element when using NWB soleus vs. control soleus nuclear extract....
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The main goal of this study was to examine the transcriptional activity of different-length beta-myosin heavy chain (beta-MHC) promoters in the hypertensive rodent heart using the direct gene transfer approach. A hypertensive state was induced by abdominal aortic constriction (AbCon) sufficient to elevate mean arterial pressure by approximately 45% relative to control. Results show that beta-MH...
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تاریخ انتشار 2001